購(gòu)物車
幫助
021-54845833/15800441009
中文名稱 : 小鼠抗ALX4單克隆抗體
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Background: |
This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq]. |
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Applications: |
WB |
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Name of antibody: |
ALX4 |
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Immunogen: |
Fusion protein of human ALX4 |
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Full name: |
ALX homeobox 4 (ALX4) |
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Synonyms: |
CRS5; FND2 |
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SwissProt: |
Q9H161 |
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WB Predicted band size: |
44 kDa |
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WB Positive control: |
Human brain tissue lysate |
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WB Recommended dilution: |
500-2000 |
